Program

Monday 13th March, 2017
Welcome and introduction of the day

Hans Peter Hartung & Avindra Nath

Mobile genetic elements and HERVs in human genomes

Hervé Perron on behalf of Cedric Feschotte

Institute of Human Genetics-Utah University, USA
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Herv copy number variation in the human population

Jainy Thomas

Institute of Human Genetics-Utah University, USA
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From HERV-W/MSRV detection in MS to preclinical models

David Kremer

Neurology Dept., Heinrich-Heine University, Düsseldorf, Germany
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MSRV-Env envelope effects on the immune system and on endothelial cells

Patrice Marche

Immunology of Chronic Diseases-INSERM, Grenoble, France
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Transcriptome analysis of MS in peripheral blood mononuclear cells and the HERV-W expression

Luiz Nali & Camila Romano

Institute of Tropical Medicine of Sao Paulo, Virology Dept., University of Sao Paulo, Brazil
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The role of repetitive elements in human psychiatric disorders

Sarven Sabuncyan

Johns Hopkins University, Baltimore, USA
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Effects of HERV-W envelope on neuronal receptors in vitro and in vivo

Laurent Groc

Dept. of Neurobiology, University of Bordeaux, France
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Coffee Break and poster session

Peter Göttle, Zelia Worman, Emily Johansson, Alexander Emmer, Ranjan Ramasamy, Holger Cynis, Mamneet Manghera, Maggie Trela, Rachel Abrams, Emanuela Balestrieri, Simone Agostini, Benjamin Charvet, Josh Dubnau

Summary of the day and facilitated discussion on science

Chair : Anthony Traboulsee & Hans Peter Hartung

Tuesday 14th March, 2017
Welcome and introduction of the day

Anthony Traboulsee & Gavin Giovannoni

Clinical trial targeting HERV-W envelope with anti-MSRV Env neutralizing humanized IgG4 in MS

Robert Glanzman on behalf of Hans Peter Hartung

Dept. of Neurology, University Hospital, Düsseldorf, Germany
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General discussion on HERV science and future clinical trials in MS

Moderators: Hans Peter Hartung and Gavin Giovannoni

Presentation of selected posters

Benjamin Charvet : International Centre for Infectiology Research, INSERM U1111, CNRS UMR5308, Ecole Normale Supérieure de Lyon, University of Lyon 1, France
Ranjan Ramasamy : ID-FISH Technology Inc
Mamneet (Sheena) Manghera : Department of Biology, University of Winnipeg
Emanuela Balistieri :University of Rome Tor vergata

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Roundtable and general discussion on HERV science: connections to current models, and novel therapeutic approaches

Moderators : Avindra Nath, Anthony Traboulsee

Panel of experts : Hans Peter Hartung, Jack Antel, Kamel Khalili¹, Lauren Bowen, Jose Flores Rivera, Guilherme Sciascia do Olival², Steven Jacobson³
Conclusions of the day

Jack Antel, Lauren Bowen, Jose Flores Rivera, Steven Jacobson, Hans Peter Hartung

1) Lewis Katz School of Medicine at Temple University, Philadelphia, USA
2) Dept. of Neurology, Albert Einstein Hospital, São Paulo, Brazil
3) NIH, Bethesda, USA

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